(19)

(11)

EP 2 126 580 A2

(12)

(88) Date of publication A3: 16.04.2009 (43) Date of publication: 02.12.2009 Bulletin 2009/49 (21) Application number: 06718094.3 (22) Date of filing: 12.01.2006

(51) International Patent Classification (IPC):  G01N 33/574(2006.01) (86) International application number: PCT/US2006/000979 (87) International publication number: WO 2006/086111 (17.08.2006 Gazette 2006/33)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) Priority: 10.02.2005 US 651583 P (71) Applicant: Cell Signaling Technology, Inc. Danvers MA 01923 (US)	(72) Inventors: GOSS, Valerie Seabrook, New Hampshire 03874 (US) MORITZ, Albrecht Salem, Massachusetts 01970 (US) GU, Ting-Lei Woburn, Massachusetts 01801 (US) LEE, Kimberly Seattle, Washington 98119 (US) POLAKIEWICZ, Roberto Lexington, Massachusetts 02421 (US) (74) Representative: Hill, Justin John et al McDermott Will & Emery UK LLP 7 Bishopsgate London EC2N 3AR London EC2N 3AR (GB)