FUSED PROTEIN CONTAINING INSULIN PRECURSOR OF OVEREXPRESSION AND SECRETION TYPE, DNA ENCODING THE SAME AND METHOD OF PRODUCING INSULIN

(19)

(11)

EP 2 128 252 A8

(12)	CORRECTED EUROPEAN PATENT APPLICATION
	published in accordance with Art. 153(4) EPC

(15)	Correction information:
	Corrected version no 1 (W1 A1)

(48)	Corrigendum issued on:
	17.03.2010 Bulletin 2010/11

(43)	Date of publication:
	02.12.2009 Bulletin 2009/49

(21)	Application number: 08711133.2

(22)	Date of filing: 12.02.2008

(51)

International Patent Classification (IPC):

C12N 15/09^(2006.01)
C12N 1/21^(2006.01)
C12P 21/06^(2006.01)

C07K 19/00^(2006.01)
C12P 21/02^(2006.01)

(86)	International application number:
	PCT/JP2008/052275

(87)	International publication number:
	WO 2009/101672 (20.08.2009 Gazette 2009/34)

(84)	Designated Contracting States:
	DE DK GB

(71)	Applicants:
	ILS INC. Moriya-shi Ibaraki 302-0104 (JP) Udaka, Shigezo Nagoya-shi, Aishi 464-0808 (JP)

(72)	Inventors:
	SATO, Seiji Ibaraki 3020104 (JP) KONDO, Masa-aki Moriya-shi, Ibaraki 302-0128 (JP) KUDO, Toshiyuki Okayama 7000812 (JP) ENDO, Ko-suke Ibaraki 3020131 (JP)

(74)	Representative: Holliday, Louise Caroline
	D Young & Co 120 Holborn London EC1N 2DY London EC1N 2DY (GB)

(54)	FUSED PROTEIN CONTAINING INSULIN PRECURSOR OF OVEREXPRESSION AND SECRETION TYPE, DNA ENCODING THE SAME AND METHOD OF PRODUCING INSULIN

(57) This invention relates to DNA encoding a fusion protein comprising highly-expressed and -secreted insulin precursors for producing recombinant insulins, and to a method for producing insulin using such DNA.