STABLE BUFFERED FORMULATIONS CONTAINING POLYPEPTIDES

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EP 2 129 401 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 2 (W2 B1)

(48)	Corrigendum issued on:
	15.01.2020 Bulletin 2020/03

(45)	Mention of the grant of the patent:
	17.07.2019 Bulletin 2019/29

(21)	Application number: 07863175.1

(22)	Date of filing: 19.12.2007

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International Patent Classification (IPC):

A61K 47/22^(2006.01)
A61K 47/18^(2017.01)

A61K 39/395^(2006.01)
A61K 9/08^(2006.01)

(86)	International application number:
	PCT/US2007/026060

(87)	International publication number:
	WO 2008/079290 (03.07.2008 Gazette 2008/27)

(54)	STABLE BUFFERED FORMULATIONS CONTAINING POLYPEPTIDES STABILE GEPUFFERTE FORMULIERUNGEN, DIE POLYPEPTIDE ENTHALTEN FORMULATIONS TAMPONNÉES STABLES CONTENANT DES POLYPEPTIDES

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
	Designated Extension States:
	AL BA HR MK RS

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Priority:

21.12.2006 US 876801 P

(43)	Date of publication of application:
	09.12.2009 Bulletin 2009/50

(73)	Proprietor: Amgen Inc.
	Thousand Oaks, California 91320-1799 (US)

(72)	Inventors:
	JACOB, Jaby Seattle, Washington 98107 (US) MATSUMURA, Masazumi Thousand Oaks, California 91320-1799 (US) GOKARN, Yatin Foster City, CA 94404 (US) BREMS, David Newburry Park, California 91320 (US)

(74)	Representative: Grünecker Patent- und Rechtsanwälte PartG mbB
	Leopoldstraße 4 80802 München 80802 München (DE)

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References cited: :

EP-A- 1 712 240
WO-A-98/14476
US-B1- 6 171 586

WO-A-96/07429
WO-A-2005/049078

Z. IGNATOVA ET AL: "Inhibition of protein aggregation in vitro and in vivo by a natural osmoprotectant" PROCEEDINGS OF TEH NATIONAL ACADEMY OF SIENCES, vol. 103, no. 36, 5 September 2006 (2006-09-05), pages 13357-13361, XP002495204 cited in the application
ARAKAWA T ET AL: "PROTEIN-SOLVENT INTERACTIONS IN PHARMACEUTICAL FORMULATIONS" PHARMACEUTICAL RESEARCH, NEW YORK, NY, US, vol. 8, no. 3, 1 January 1991 (1991-01-01), pages 285-291, XP009052919 ISSN: 0724-8741

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).