(19)

(11)

EP 2 136 845 A2

(12)

(88) Date of publication A3: 30.04.2009 (43) Date of publication: 30.12.2009 Bulletin 2009/53 (21) Application number: 08718733.2 (22) Date of filing: 14.03.2008

(51) International Patent Classification (IPC):  A61K 47/48(2006.01) C07C 69/16(2006.01) A61K 9/00(2006.01) C07C 43/20(2006.01) C07D 407/04(2006.01) (86) International application number: PCT/GB2008/000891 (87) International publication number: WO 2008/110813 (18.09.2008 Gazette 2008/38)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR (30) Priority: 15.03.2007 GB 0705023 (71) Applicant: The Nottingham Trent University Nottingham NG11 8NS (GB)	(72) Inventor: DAVIS, James Nottingham NG11 8NS (GB) (74) Representative: Elsy, David  Withers & Rogers LLP LSC 2 Hays lane London SE1 2HW London SE1 2HW (GB)