(19)

(11)

EP 2 137 216 A2

(12)

(88) Date of publication A3: 31.12.2008 (43) Date of publication: 30.12.2009 Bulletin 2009/53 (21) Application number: 08726797.7 (22) Date of filing: 12.03.2008

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) A61K 39/395(2006.01) C07K 16/00(2006.01) C12N 15/11(2006.01) A61P 35/00(2006.01) (86) International application number: PCT/US2008/003355 (87) International publication number: WO 2008/112290 (18.09.2008 Gazette 2008/38)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 12.03.2007 US 906764 P 12.03.2007 US 906727 P (71) Applicants: Vasgene Therapeutics, Inc. Sharon Hill, PA 19079 (US) Board of Regents of the University of Texas System Austin, TX 78701 (US)	(72) Inventors: KRASNOPEROV, Valery South Pasadena, CA 91030 (US) GILL, Parkash Agoura Hills, CA 91301 (US) SOOD, Anil, K. Pearland, TX 77584 (US) (74) Representative: Lee, Nicholas John et al Kilburn & Strode LLP 20 Red Lion Street London WC1R 4PJ London WC1R 4PJ (GB)