(19)

(11)

EP 2 142 090 A2

(12)

(88) Date of publication A3: 08.01.2009 (43) Date of publication: 13.01.2010 Bulletin 2010/02 (21) Application number: 08769256.2 (22) Date of filing: 30.04.2008

(51) International Patent Classification (IPC):  A61B 5/055(2006.01) G01R 33/20(2006.01) (86) International application number: PCT/US2008/062115 (87) International publication number: WO 2008/137485 (13.11.2008 Gazette 2008/46)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR (30) Priority: 04.05.2007 US 927706 P 18.12.2007 US 8127 (71) Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY Pasadena, CA 91125 (US)	(72) Inventors: PENANEN, Konstantin I. Glendale, California 91207 (US) EOM, Byeong H. Pasadena, California 91109 (US) HAHN, Inseob La Crescenta, California 91214 (US) (74) Representative: Papa, Elisabetta  Società Italiana Brevetti S.p.A Piazza di Pietra, 39 00186 Roma 00186 Roma (IT)