(19)
(11) EP 2 142 543 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
03.07.2013 Bulletin 2013/27

(45) Mention of the grant of the patent:
22.05.2013 Bulletin 2013/21

(21) Application number: 08742815.7

(22) Date of filing: 11.04.2008
(51) International Patent Classification (IPC): 
C07D 471/04(2006.01)
A61P 35/00(2006.01)
 A61K 31/519(2006.01)
(86) International application number:
PCT/US2008/004753
(87) International publication number:
WO 2008/127678 (23.10.2008 Gazette 2008/43)

(54)

PYRIDO [2, 3-D]PYRIMIDIN-7-ONE COMPOUNDS AS INHIBITORS OF PI3K-ALPHA FOR THE TREATMENT OF CANCER

PYRIDO [2,3-D]PYRIMIDIN-7-ONVERBINDUNGEN ALS INHIBITOREN VON PI3K-ALPHA ZUR BEHANDLUNG VON KREBS

COMPOSÉS PYRIDO [2, 3-D]PYRIMIDIN-7-ONE UTILISÉS EN TANT QU'INHIBITEURS DE PI3K-ALPHA POUR LE TRAITEMENT DU CANCER

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
Designated Extension States:
AL BA MK RS

(30) Priority: 11.04.2007 US 911189 P

(43) Date of publication of application:
13.01.2010 Bulletin 2010/02

(73) Proprietor: Exelixis, Inc.
South San Francisco, CA 94080 (US)

(72) Inventors:
  • BUHR, Chris A.
    Redwood City, California 94061 (US)
  • BAJJALIEH, William
    San Francisco, California 94116 (US)
  • JOSHI, Anagha Abhijit
    Fremont, California 94536 (US)
  • LARA, Katherine
    San Mateo, California 94403 (US)
  • MA, Sunghoon
    Foster City, California 94404 (US)
  • MARLOWE, Charles K.
    Emerald Hills, California 94062 (US)
  • WANG, Longcheng
    Palo Alto, California 94306 (US)
  • YEUNG, Bryan K. S.
    Chromos 138670 (SG)

(74) Representative: Main, Malcolm Charles 
Murgitroyd & Company Immeuble Atlantis 55 Allee Pierre Ziller
06560 Valbonne - Sophia Antipolis
06560 Valbonne - Sophia Antipolis (FR)


(56) References cited: : 
WO-A-96/34867
WO-A-2008/021389
US-A1- 2004 009 993
 WO-A-2005/105801
WO-A1-2007/044698
   
       
    Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).