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EP 2 142 649 A2

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(88) Date of publication A3: 02.04.2009 (43) Date of publication: 13.01.2010 Bulletin 2010/02 (21) Application number: 08736900.5 (22) Date of filing: 07.04.2008

(51) International Patent Classification (IPC):  C12N 15/11(2006.01) A61K 31/713(2006.01) C07K 5/06(2006.01) C12Q 1/37(2006.01) (86) International application number: PCT/GB2008/001223 (87) International publication number: WO 2008/122794 (16.10.2008 Gazette 2008/42)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR (30) Priority: 05.04.2007 GB 0706658 (71) Applicant: Imperial Innovations Limited Imperial College London SW7 2AZ (GB)	(72) Inventors: SLADE, Martin 5th Floor MRC Cyclotron Building Du Cane Road London W12 0NN (GB) COOMBES, Raoul, Charles 5th Floor MRC Cyclotron Building Du Cane Road London W12 0NN (GB) (74) Representative: Pilkington, Stephanie Joan et al Potter Clarkson LLP Park View House 58 The Ropewalk Nottingham NG1 5DD Nottingham NG1 5DD (GB)