USE OF AN ASPARTIC PROTEASE (NSP24) SIGNAL SEQUENCE FOR HETEROLOGOUS PROTEIN EXPRESSION

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EP 2 147 104 A1

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(43)	Date of publication:
	27.01.2010 Bulletin 2010/04

(21)	Application number: 08754611.5

(22)	Date of filing: 21.05.2008

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International Patent Classification (IPC):

C12N 15/62^(2006.01)
C12N 9/16^(2006.01)
C12P 21/02^(2006.01)

C12N 9/02^(2006.01)
C12N 9/58^(2006.01)

(86)	International application number:
	PCT/US2008/006498

(87)	International publication number:
	WO 2008/150376 (11.12.2008 Gazette 2008/50)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
	Designated Extension States:
	AL BA MK RS

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Priority:

21.05.2007 US 931072 P
01.11.2007 US 984430 P
06.02.2008 WO PCT/US2008/000164

(71)	Applicant: Danisco US, Inc., Genencor Division
	Palo Alto, CA 94304 (US)

(72)	Inventors:
	CERVIN, Marguerite A. Palo Alto, California 94304 (US) KIM, Steven Palo Alto, California 94304 (US)

(74)	Representative: Kiddle, Simon John et al
	Mewburn Ellis LLP 33 Gutter Lane London EC2V 8AS London EC2V 8AS (GB)

(54)	USE OF AN ASPARTIC PROTEASE (NSP24) SIGNAL SEQUENCE FOR HETEROLOGOUS PROTEIN EXPRESSION