| (84) |
Designated Contracting States: |
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AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL
PT RO SE SI SK TR |
| (30) |
Priority: |
01.05.2007 US 915247 P
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| (43) |
Date of publication of application: |
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17.02.2010 Bulletin 2010/07 |
| (73) |
Proprietors: |
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- Fundação de Amparo à Pesquisa do Estado de São
Paulo - FAPESP
05468-901 São Paulo (BR)
- Biolab Sanus Farmacêutica Ltda.
06767-220, Taboão da Serra, São Paulo (BR)
- Cury, Yara
06539-045 São Paulo SP (BR)
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| (72) |
Inventors: |
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- CURY, Yara
Santana de Parnaíba,
06539-045 Sao Paulo SP (BR)
- PICOLO, Gisele
03411-120 São Paulo - Sp (BR)
- KONNO, Katsuhiro
Santo Domingo (DO)
|
| (74) |
Representative: Kling, Simone et al |
|
Lavoix Munich
Bayerstrasse 83 80335 München 80335 München (DE) |
| (56) |
References cited: :
WO-A2-2005/107357
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US-A- 5 232 911
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- ALLAN, L. ET AL: "The complete sequence of the acidic subunit from Mojave toxin determined
by Edman degradation and mass spectrometry" BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1037,
1990, pages 413-421, XP002577748
- FAURE G. ET AL.: 'Multiplicity of acidic subunit isoforms of crotoxin, the phospholipase
A2 neurotoxin from Crotalus durissus terrificus venom, results from posttranslational
modifications' BIOCHEMISTRY vol. 30, no. 32, 13 August 1991, pages 8074 - 8083, XP002476828
- AIRD S.D. ET AL.: 'Rattlesnake presynaptic neurotoxins: primary structure and evolutionary
origin of the acidic subunit' BIOCHEMISTRY vol. 24, no. 25, 03 December 1985, pages
7054 - 7058, XP002476827
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