(19)

(11)

EP 2 155 667 A1

(12)

(43) Date of publication: 24.02.2010 Bulletin 2010/08 (21) Application number: 08780784.8 (22) Date of filing: 09.06.2008

(51) International Patent Classification (IPC):  C07D 205/08(2006.01) (86) International application number: PCT/US2008/066351 (87) International publication number: WO 2008/151324 (11.12.2008 Gazette 2008/50)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 07.06.2007 US 933837 P 11.09.2007 US 971504 P 28.11.2007 US 4725 (71) Applicant: Teva Pharmaceutical Industries Ltd. 49131 Petah Tiqva (IL)	(72) Inventors: PERLMAN, Nurit 44539 Kfar Saba (IL) FISHMAN, Ayelet 34814 Haifa (IL) (74) Representative: Clarke, Lionel Paul  Gill Jennings & Every LLP Broadgate House 7 Eldon Street London EC2M 7LH 7 Eldon Street London EC2M 7LH (GB)