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EP 2 155 687 A1

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(43) Date of publication: 24.02.2010 Bulletin 2010/08 (21) Application number: 08759547.6 (22) Date of filing: 13.05.2008

(51) International Patent Classification (IPC):  C07D 231/14(2006.01) C07D 277/56(2006.01) C07D 401/12(2006.01) C07D 409/14(2006.01) C07D 413/14(2006.01) A61K 31/422(2006.01) A61K 31/4178(2006.01) A61K 31/4427(2006.01) C07D 263/34(2006.01) C07D 307/68(2006.01) C07D 401/14(2006.01) C07D 413/12(2006.01) C07D 417/14(2006.01) A61K 31/427(2006.01) A61K 31/4192(2006.01) (86) International application number: PCT/EP2008/055843 (87) International publication number: WO 2008/141976 (27.11.2008 Gazette 2008/48)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 22.05.2007 US 931303 P 22.05.2007 US 931273 P 22.05.2007 US 931327 P 22.05.2007 US 931369 P (71) Applicant: Via Pharmaceuticals, Inc. San Francisco, CA 94111 (US)

(72) Inventors: BOLIN, David Robert Montclair, New Jersey 07042 (US) CHEUNG, Adrian Wai-Hing Glen Rock, New Jersey 07452 (US) FIROOZNIA, Fariborz Florham Park, New Jersey 07932 (US) HAMILTON, Matthew Michael Hackettstown, New Jersey 07840 (US) MCDERMOTT, Lee Apostle Parlin, New Jersey 08859 (US) QIAN, Yimin Wayne, New Jersey 07470 (US) TAN, Jenny New Providence, New Jersey 07974 (US) YUN, Weiya Warren, New Jersey 07059 (US) (74) Representative: Bohest AG  Postfach 160 CH-4003 Basel CH-4003 Basel (CH)