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(11)

EP 2 160 411 A1

(12)

(43) Date of publication: 10.03.2010 Bulletin 2010/10 (21) Application number: 08774371.2 (22) Date of filing: 26.06.2008

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) C12N 15/13(2006.01) A61K 39/395(2006.01) C07K 16/46(2006.01) C12N 5/20(2006.01) A61P 7/00(2006.01) (86) International application number: PCT/EP2008/058196 (87) International publication number: WO 2009/000894 (31.12.2008 Gazette 2009/01)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 26.06.2007 US 946168 P 29.06.2007 EP 07012752 (71) Applicants: ThromboGenics N.V. 3001 Heverlee (BE) Life Sciences Research Partners VZW 3000 Leuven (BE)	(72) Inventors: FRESON, Kathleen B-3730 Hoeselt (BE) VAN GEET, Chris B-3221 Nieuwrode (BE) HOYLAERTS, Marc B-3010 Kessel-Lo (BE) STASSEN, Jean-Marie B-3210 Lubbeek (BE) (74) Representative: Bird, William Edward et al Bird Goën & Co. Klein Dalenstraat 42A 3020 Winksele 3020 Winksele (BE)