ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCYALTRBGCZEEHUPLSKBAHRIS..MTNORS..SM..................JDIM360 Ver 2.15 (14 Jul 2008) - 1620000/02163542EUROPEAN PATENT APPLICATIONA320121219EP09169837.320090909enenen2008008895520080909KR2012121920125120100317201011C07D 213/40 20060101AFI20121115BHEP C12N 15/10 20060101ALI20121115BHEP B01J 43/00 20060101ALI20121115BHEP B01J 39/18 20060101ALI20121115BHEP B01J 41/12 20060101ALI20121115BHEP deBi-funktionale, positiv geladene Verbindung bei einem ersten pH-Wert und negativ geladen bei einem zweiten pH-Wert, Festkörperträger mit der bi-funktionalen Verbindung und Verfahren zur Isolierung von Nukleinsäure damitenBi-functional compound positively charged at first pH and negatively charged at second pH, solid support comprising the bi-functional compound, and method of isolating nucleic acid using the samefrComposé bifonctionnel à charge positive à un premier pH et à charge négative à un deuxième pH, support solide comprenant le composé bifonctionnel et procédé d'isolement d'acide nucléique l'utilisantSamsung Electronics Co., Ltd.101328413EP66858KG900hau129, Samsung-ro Yeongtong-guSuwon-si, Gyeonggi-do, 443-742KRHwang, Kyu-younc/o Samsung Advanced Institute of Technology San 14-1 Nongseo-dong Giheung-gu, Yongin-siGyeonggi-doKRKim, Joon-hoc/o Samsung Advanced Institute of Technology San 14-1 Nongseo-dong Giheung-gu, Yongin-siGyeonggi-doKRGrünecker, Kinkeldey, Stockmair & Schwanhäusser100060488Leopoldstrasse 480802 MünchenDEATBEBGCHCYCZDEDKEEESFIFRGBGRHRHUIEISITLILTLULVMCMKMTNLNOPLPTROSESISKSMTRALBARS20121219201251

Provided are a bi-functional compound that is positively charged at a first pH and negatively charged at a second pH, a solid support having the bi-functional compound immobilized thereon, and a method of isolating a nucleic acid, including: binding the bi-functional compound with a nucleic acid at a first pH and isolating the nucleic acid from the bi-functional compound at a second pH.

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