(19)

(11)

EP 2 164 997 A2

(12)

(88) Date of publication A3: 22.05.2009 (43) Date of publication: 24.03.2010 Bulletin 2010/12 (21) Application number: 08826008.8 (22) Date of filing: 10.04.2008

(51) International Patent Classification (IPC):  C12Q 1/68(2006.01) G01N 33/53(2006.01) (86) International application number: PCT/US2008/059963 (87) International publication number: WO 2009/005871 (08.01.2009 Gazette 2009/02)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 10.04.2007 US 911051 P 07.05.2007 US 916548 P (71) Applicant: Montana State University Bozeman, MT 59717-2460 (US)	(72) Inventors: DRATZ, Edward .Bozeman, MT 59715 (US) GRIECO, Paul Bozeman, MT 59715 (US) (74) Representative: Vossius & Partner  Siebertstraße 4 81675 München 81675 München (DE)