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EP 2 167 508 A1

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(43) Date of publication: 31.03.2010 Bulletin 2010/13 (21) Application number: 08776016.1 (22) Date of filing: 21.07.2008

(51) International Patent Classification (IPC):  C07D 498/04(2006.01) A61K 31/4196(2006.01) A61K 31/429(2006.01) C07D 513/04(2006.01) A61K 31/423(2006.01) A61P 21/00(2006.01) (86) International application number: PCT/GB2008/002495 (87) International publication number: WO 2009/013477 (29.01.2009 Gazette 2009/05)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 23.07.2007 GB 0714303 03.03.2008 GB 0803906 (71) Applicant: Summit Corporation Plc Abingdon Oxfordshire OX14 4RY (GB)	(72) Inventors: WYNNE, Graham, Michael Oxfordshire OX14 4RY (GB) WREN, Stephen, Paul Oxfordshire OX14 4RY (GB) PRICE, Paul, Damien Oxfordshire OX14 4RY (GB) (74) Representative: Jones Day  Rechtsanwälte, Attorneys-at-Law, Patentanwälte Prinzregentenstrasse 11 80538 München 80538 München (DE)