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(11)

EP 2 167 539 A2

(12)

(88) Date of publication A3: 03.09.2009 (43) Date of publication: 31.03.2010 Bulletin 2010/13 (21) Application number: 08773472.9 (22) Date of filing: 16.06.2008

(51) International Patent Classification (IPC):  C07K 14/81(2006.01) (86) International application number: PCT/EP2008/004844 (87) International publication number: WO 2008/151845 (18.12.2008 Gazette 2008/51)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 15.06.2007 US 944232 P (71) Applicants: Charité - Universitätsmedizin Berlin 10117 Berlin (DE) ProBioGen AG 13086 Berlin (DE)

(72) Inventors: BERGER, Markus 12209 Berlin (DE) MARX, Uwe 13129 Berlin (DE) SANDIG, Volker 13185 Berlin (DE) BRECHT, René 13156 Berlin (DE) KOCH, Susann 15345 Eggersdorf (DE) AMMER, Richard 10405 Berlin (DE) RIECK, Silke 13187 Berlin (DE) REUTTER, Werner 14195 Berlin (DE) BLANCHARD, Veronique 10559 Berlin (DE) KAUP, Matthias 13437 Berlin (DE) TAUBER, Rudolf 14163 Berlin (DE) ZIETZE, Stefan 16775 Falkenthal (DE) (74) Representative: Engelhard, Markus  Forrester & Boehmert Pettenkoferstrasse 20-22 80366 München 80366 München (DE)