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(11)

EP 2 170 891 A1

(12)

(43) Date of publication: 07.04.2010 Bulletin 2010/14 (21) Application number: 08760162.1 (22) Date of filing: 28.05.2008

(51) International Patent Classification (IPC):  C07D 487/04(2006.01) A61K 31/44(2006.01) A61K 31/519(2006.01) A61P 35/00(2006.01) (86) International application number: PCT/EP2008/056569 (87) International publication number: WO 2008/145678 (04.12.2008 Gazette 2008/49)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 29.05.2007 US 932155 P 26.07.2007 EP 07113226 (71) Applicant: Agennix AG 69120 Heidelberg (DE)	(72) Inventor: KLUGE, Arthur F. Lincoln, Massachusetts 01773 (US) (74) Representative: Virnekäs, Bernhard  Wallinger Ricker Schlotter Foerstl Patent- und Rechtsanwälte Zweibrückenstrasse 5-7 80331 München 80331 München (DE)