(19)

(11)

EP 2 170 929 A2

(12)

(88) Date of publication A3: 26.02.2009 (43) Date of publication: 07.04.2010 Bulletin 2010/14 (21) Application number: 08772440.7 (22) Date of filing: 07.07.2008

(51) International Patent Classification (IPC):  C07K 7/06(2006.01) A61K 38/08(2006.01) C07H 21/04(2006.01) C12N 1/19(2006.01) C07K 14/43(2006.01) A61K 39/395(2006.01) C12N 15/11(2006.01) (86) International application number: PCT/US2008/069365 (87) International publication number: WO 2009/006638 (08.01.2009 Gazette 2009/02)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 05.07.2007 US 948130 P (71) Applicants: Dart Neurosciences, LLC San Diego, CA 92121 (US) Bearer, Elaine L. 9 Diman Place Providence, RI 02906 (US)	(72) Inventor: BEARER, Elaine, L. Providence, RI 02906 (US) (74) Representative: Becker, Philippe et al Cabinet Becker & Associés 25, rue Louis Le Grand 75002 Paris 75002 Paris (FR)