(19)

(11)

EP 2 178 588 A1

(12)

(43) Date of publication: 28.04.2010 Bulletin 2010/17 (21) Application number: 08781677.3 (22) Date of filing: 11.07.2008

(51) International Patent Classification (IPC):  A61M 15/00(2006.01) (86) International application number: PCT/US2008/069759 (87) International publication number: WO 2009/012137 (22.01.2009 Gazette 2009/04)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 19.07.2007 US 880217 (71) Applicant: Laboratoire Tradiphar 59000 Lille (FR)	(72) Inventor: LOCKWOOD JR., Hanford N. San Mateo, California 94403 (US) (74) Representative: Matkowska, Franck  Matkowska & Associés 9 Rue Jacques Prévert 59650 Villeneuve d'Ascq 59650 Villeneuve d'Ascq (FR)