(19)

(11)

EP 2 178 911 A2

(12)

(88) Date of publication A3: 30.04.2009 (43) Date of publication: 28.04.2010 Bulletin 2010/17 (21) Application number: 08803019.2 (22) Date of filing: 12.08.2008

(51) International Patent Classification (IPC):  C07K 14/62(2006.01) (86) International application number: PCT/EP2008/060597 (87) International publication number: WO 2009/021956 (19.02.2009 Gazette 2009/08)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 13.08.2007 EP 07114216 (71) Applicant: Novo Nordisk A/S 2880 Bagsværd (DK)	(72) Inventors: OLSEN, Helle, Birk DK-3450 Allerød (DK) KJELDSEN, Thomas, Børglum DK-2830 Virum (DK) BALSCHMIDT, Per DK-2970 Hørsholm (DK) GLENDORF, Tine DK-2800 Kgs Lyngby (DK) HAVELUND, Svend DK-2800 Bagsværd (DK)