(19)
(11) EP 2 179 035 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
03.04.2013 Bulletin 2013/14

(45) Mention of the grant of the patent:
27.02.2013 Bulletin 2013/09

(21) Application number: 08786965.7

(22) Date of filing: 06.08.2008
(51) International Patent Classification (IPC): 
C12N 7/00(2006.01)
A61K 35/76(2006.01)
A01N 63/00(2006.01)
(86) International application number:
PCT/EP2008/060360
(87) International publication number:
WO 2009/019293 (12.02.2009 Gazette 2009/07)

(54)

MODIFIED BACTERIOPHAGE INCLUDING AN ALPHA/BETA SMALL ACID-SOLUBLE SPORE PROTEIN (SASP) GENE

MODIFIZIERTER BAKTERIOPHAGE MIT EINEM ALPHA/BETA-SASP-(SMALL ACID-SOLUBLE SPORE PROTEIN-)-GEN

BACTÉRIOPHAGE MODIFIÉ PAR MOYEN D'UN GÈNE ALPHA/BETA SASP (SMALL ACID-SOLUBLE SPORE PROTEIN)


(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

(30) Priority: 07.08.2007 GB 0715416

(43) Date of publication of application:
28.04.2010 Bulletin 2010/17

(73) Proprietor: Phico Therapeutics Ltd
Cambridge, Cambridgeshire CB2 4AT (GB)

(72) Inventors:
  • FAIRHEAD, Heather
    Cambridge CB24 9JU (GB)
  • WILKINSON, Adam
    Saffron Walden CB11 4EX (GB)
  • HOLME, Sarah
    Royston, Hertfordshire SG8 7AU (GB)
  • PITTS, Katy
    Cambridge CB22 7AB (GB)
  • JACKSON, Alison
    Lauder, Berwickshire TD2 6PA (GB)

(74) Representative: Daniels, Jeffrey Nicholas 
Page White & Farrer Bedford House John Street
London WC1N 2BF
London WC1N 2BF (GB)


(56) References cited: : 
WO-A-02/40678
WO-A-2004/113375
   
  • A. BARNARD, K. PITTS, D. BROWN, A. WILKINSON, H. FAIRHEAD: "SASP: rapid bactericidal activity against USA strains of meticillin-resistant Staphylococcus aureus" CLINICAL MICROBIOLOGY AND INFECTION, [Online] vol. 14, no. s7, 7 April 2008 (2008-04-07), pages S131-S132, XP002505321 ISSN: 1198-743X Retrieved from the Internet: URL:http://dx.doi.org/10.1111/j.1469-0691. 2008.02007.x> [retrieved on 2008-11-24]
  • HANLON ET AL: "Bacteriophages: an appraisal of their role in the treatment of bacterial infections" INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, ELSEVIER SCIENCE, AMSTERDAM, NL, vol. 30, no. 2, 27 June 2007 (2007-06-27), pages 118-128, XP022132522 ISSN: 0924-8579
  • SETLOW J K ET AL: "MUTATION AND KILLING OF ESCHERICHIA COLI EXPRESSING A CLONED BACILLUS SUBTILIS GENE WHOSE PRODUCT ALTERS DNA CONFORMATION" JOURNAL OF BACTERIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 174, no. 9, 1 May 1992 (1992-05-01), pages 2943-2950, XP001002852 ISSN: 0021-9193
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).