(19)

(11)

EP 2 183 202 A2

(12)

(88) Date of publication A3: 16.04.2009 (43) Date of publication: 12.05.2010 Bulletin 2010/19 (21) Application number: 08796340.1 (22) Date of filing: 18.07.2008

(51) International Patent Classification (IPC):  C07B 59/00(2006.01) B01D 59/40(2006.01) (86) International application number: PCT/US2008/070558 (87) International publication number: WO 2009/015048 (29.01.2009 Gazette 2009/05)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 20.07.2007 US 950976 P (71) Applicants: Siemens Medical Solutions USA, Inc. Malvern, PA 19355-1406 (US) Materia, Inc. Pasadena, CA 91107 (US) California Institute of Technology Pasadena, CA 91125 (US)

(72) Inventors: ELIZAROV, Arkadij M. Valley Village, CA 91607 (US) KOLB, Hartmuth, C. Playa Del Rey, CA 90293 (US) VAN DAM, R. Michael Glendale, CA 91206 (US) HEATH, James, R. South Pasadena, CA 91030 (US) EDGECOMBE, Brian Anaheim, CA 92807 (US) MOTAMEDI, Farshad Claremont, CA 91711 (US) STEPHEN, Anthony South Pasadena, CA 91030 (US) GIARDELLO, Michael A. Pasadena, CA 91106 (US) (74) Representative: Brocklehurst, Adam Jeffrey et al Siemens AG Postfach 22 16 34 80506 München 80506 München (DE)