(19)
(11) EP 2 184 984 A1

(12)

(43) Date of publication:
19.05.2010 Bulletin 2010/20

(21) Application number: 08796733.7

(22) Date of filing: 28.07.2008
(51) International Patent Classification (IPC): 
A01N 41/06(2006.01)
A61K 31/18(2006.01)
(86) International application number:
PCT/US2008/071392
(87) International publication number:
WO 2009/018233 (05.02.2009 Gazette 2009/06)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
Designated Extension States:
AL BA MK RS

(30) Priority: 30.07.2007 US 830733
06.03.2008 US 34466
06.03.2008 US 34464
14.04.2008 US 44886

(71) Applicant: Ardea Biosciences, Inc.
San Diego, CA 92121 (US)

(72) Inventors:
  • VERNIER, Jean-michel
    Laguna Niguel, CA 92677 (US)
  • ROWLINGS, Colin, Edward
    Encinitas, CA 92024 (US)
  • GIRARDET, Jean-luc
    San Diego, CA 92127 (US)
  • DIMOCK, Stuart
    Lake Forest, CA 92630 (US)
  • QUART, Barry
    Encinitas, CA 92024 (US)
  • MINER, Jeffrey, N.
    San Diego, CA 92122 (US)

(74) Representative: Williams, Paul Howard 
Bayer Schering Pharma AG BPA-LP-PL Patents Counsels <Z> Geb.: S105 / 640 BLN BLN
13353 Berlin
13353 Berlin (DE)

   


(54) DERIVATIVES OF N-(ARYLAMINO) SULFONAMIDES INCLUDING POLYMORPHS AS INHIBITORS OF MEK AS WELL AS COMPOSITIONS, METHODS OF USE AND METHODS FOR PREPARING THE SAME