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(11)

EP 2 185 059 A1

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(43) Date of publication: 19.05.2010 Bulletin 2010/20 (21) Application number: 07814757.6 (22) Date of filing: 07.09.2007

(51) International Patent Classification (IPC):  A61B 1/00(2006.01) A61B 5/05(2006.01) A61B 1/04(2006.01) (86) International application number: PCT/US2007/077938 (87) International publication number: WO 2009/032016 (12.03.2009 Gazette 2009/11)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (71) Applicant: University of Washington Seattle, WA 98105-4608 (US)	(72) Inventors: SEIBEL, Eric J. Seattle, Washington 98117 (US) JOHNSTON, Richard S. Sammamish, Washington 98075 (US) (74) Representative: Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät  Leopoldstrasse 4 80802 München 80802 München (DE)