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EP 2 195 422 A1

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(43) Date of publication: 16.06.2010 Bulletin 2010/24 (21) Application number: 08742666.4 (22) Date of filing: 08.04.2008

(51) International Patent Classification (IPC):  C12N 9/34(2006.01) C12N 15/56(2006.01) C12R 1/885(2006.01) C07K 14/37(2006.01) C12N 15/31(2006.01) C12N 15/62(2006.01) (86) International application number: PCT/US2008/004556 (87) International publication number: WO 2009/048487 (16.04.2009 Gazette 2009/16)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 09.10.2007 WO PCT/US2007/021683 (71) Applicant: Danisco US Inc. Palo Alto, CA 94304 (US)

(72) Inventors: AEHLE, Wolfgang Palo Alto, California 94304 (US) BOTT, Richard R. Palo Alto, California 94304 (US) NIKOLAEV, Igor Palo Alto, California 94304 (US) SCHEFFERS, Martijn Palo Alto, California 94304 (US) VAN SOLINGEN, Piet Palo Alto, California 94304 (US) VROEMEN, Casper Palo Alto, California 94304 (US) (74) Representative: Forrest, Graham Robert et al Mewburn Ellis LLP 33 Gutter Lane London EC2V 8AS London EC2V 8AS (GB)