(19)

(11)

EP 2 197 885 A1

(12)

(43) Date of publication: 23.06.2010 Bulletin 2010/25 (21) Application number: 08802109.2 (22) Date of filing: 10.09.2008

(51) International Patent Classification (IPC):  C07D 493/20(2006.01) A61P 33/06(2006.01) A61K 31/365(2006.01) (86) International application number: PCT/EP2008/007556 (87) International publication number: WO 2009/033706 (19.03.2009 Gazette 2009/12)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 10.09.2007 WO PCT/EP2007/007868 (71) Applicant: Dafra Pharma N.V. 2300 Turnhout (BE)	(72) Inventors: JANSEN, Frans Herwing B-2360 Oud-Thurnout (BE) SOOMRO, Shahid Ahmed B-2300 Turnhout (BE) (74) Representative: van Kooij, Adriaan et al Arnold & Siedsma Sweelickplein 1 2517 GK Den Haag 2517 GK Den Haag (NL)