(19)

(11)

EP 2 200 627 A1

(12)

(43) Date of publication: 30.06.2010 Bulletin 2010/26 (21) Application number: 07814876.4 (22) Date of filing: 14.09.2007

(51) International Patent Classification (IPC):  A61K 38/00(2006.01) C07K 7/00(2006.01) (86) International application number: PCT/US2007/078550 (87) International publication number: WO 2009/035460 (19.03.2009 Gazette 2009/12)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (71) Applicants: University of Medicine and Dentistry of New Jersey Suite 3200, 335 George Street New Brunswick, NJ 08901 (US) Rutgers, The State University of New Jersey New Brunswick, NJ 08909 (US)	(72) Inventors: GOYDOS, James, S. East Brunswick, NJ 08816 (US) CHEN, Suzie Highland Park, NJ 08904 (US) (74) Representative: Viering, Jentschura & Partner  Grillparzerstrasse 14 81675 München 81675 München (DE)