| (84) |
Designated Contracting States: |
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AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL
PT RO SE SI SK TR |
| (30) |
Priority: |
17.09.2007 US 960128 P
|
| (43) |
Date of publication of application: |
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30.06.2010 Bulletin 2010/26 |
| (73) |
Proprietor: MDxHealth SA |
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4040 HERSTAL (BE) |
|
| (72) |
Inventors: |
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- VLASSENBROECK, Ilse
B-4000 Sart-Tilman (BE)
- BIERAU, Katja
B-4000 Sart-Tilman (BE)
|
| (74) |
Representative: Boult Wade Tennant |
|
Verulam Gardens
70 Gray's Inn Road
London WC1X 8BT
London WC1X 8BT (GB) |
| (56) |
References cited: :
WO-A-2004/087957
WO-A-2008/084219
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WO-A-2005/042713
US-A- 6 090 552
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- REIMO TETZNER: "Entwicklung von Realtime-PCR-Methoden. zur Analyse von DNA-Methylierung"[Online]
2006, pages 1-122, XP002511168 Retrieved from the Internet: URL:http://scidok.sulb.uni-saarland.de/vol
ltexte/2007/1127/pdf/Tetzner_Reimo_Dissert ation_2007.pdf> [retrieved on 2009-01-20]
- ANDREAS M RICKERT ET AL: "Refinement of single-nucleotide polymorphism genotyping
methods on human genomic DNA: amplifluor allele-specific polymerase chain reaction
versus ligation detection reaction-TaqMan" ANALYTICAL BIOCHEMISTRY, vol. 330, no.
2, 2006, pages 288-297, XP002511169
- MAXWELL JILL A ET AL: "Quantitative analysis of O6-alkylguanine-DNA alkyltransferase
in malignant glioma." MOLECULAR CANCER THERAPEUTICS OCT 2006, vol. 5, no. 10, October
2006 (2006-10), pages 2531-2539, XP002511170 ISSN: 1535-7163
- HOUSE MICHAEL G ET AL: "Molecular progression of promoter methylation in intraductal
papillary mucinous neoplasms (IPMN) of the pancreas." CARCINOGENESIS FEB 2003, vol.
24, no. 2, February 2003 (2003-02), pages 193-198, XP002511171 ISSN: 0143-3334
- CALIFICE ET AL: "A new method for testing MGMT gene promoter methylation status of
glioblastoma tissue using a direct. real-time fluorescence-based methylation-specific
PCR"[Online] June 2007 (2007-06), XP002511172 2nd International Conference on MGMT,
Mainz, Germany Retrieved from the Internet: URL:http://www.oncomethylome.com/newsroom/
documents/2007June13_MGMT_001.pdf> [retrieved on 2009-01-20] & POSTER NUMBER 4:[Online]
June 2007 (2007-06), pages 77-78, Retrieved from the Internet: URL:http://www.mgmt-agt.net/Abstract%20boo
k%20for%20MGMT%20webpage.pdf> [retrieved on 2009-01-20]
- ESTELLER MANEL ET AL: "Hypermethylation of the DNA repair gene O(6)-methylguanine
DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma."
JOURNAL OF THE NATIONAL CANCER INSTITUTE 2 JAN 2002, vol. 94, no. 1, 2 January 2002
(2002-01-02), pages 26-32, XP002511173 ISSN: 0027-8874
- VLASSENBROECK I ET AL: "Validation of real-time methylation-specific PCR to determine
O <6>-methylguanine-DNA methyltransferase gene promoter methylation in glioma" JOURNAL
OF MOLECULAR DIAGNOSTICS, AMERICAN SOCIETY FOR INVESTIGATIVE PATHOLOGY, BETHESDA,
MD, US, vol. 10, no. 4, 1 January 2008 (2008-01-01), pages 332-337, XP009110852 ISSN:
1525-1578
- DEMING KONG ET AL: "Real-time PCR detection of telomerase activity using specific
molecular beacon probes", ANALYTICAL AND BIOANALYTICAL CHEMISTRY, SPRINGER, BERLIN,
DE, vol. 388, no. 3, 17 April 2007 (2007-04-17), pages 699-709, XP019512336, ISSN:
1618-2650, DOI: 10.1007/S00216-007-1247-6
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