(19)

(11)

EP 2 201 353 A1

(12)

(43) Date of publication: 30.06.2010 Bulletin 2010/26 (21) Application number: 08833371.1 (22) Date of filing: 26.09.2008

(51) International Patent Classification (IPC):  G01N 23/223(2006.01) (86) International application number: PCT/US2008/077971 (87) International publication number: WO 2009/042932 (02.04.2009 Gazette 2009/14)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 28.09.2007 US 995997 P (71) Applicant: Caldera Pharmaceuticals, Inc. Los Alamos, NM 87544 (US)

(72) Inventors: BIRNBAUM, Eva, R. Los Alamos NM 87544 (US) WARNER, Benjamin, P. Tucson AZ 87544 (US) BALDWIN, Sharon, M. Santa Fe NM 87507 (US) BERGER, Jennifer, A. Los Alamos NM 87544 (US) PETERSON-COURT, Lori, J. Los Alamos NM 85744 (US) HARRIS, Michael, N. Tucson AZ 87544 (US) MILLER, Rebecca, L.E. Los Alamos NM 87507 (US) (74) Representative: Snodin, Michael D.  Potter Clarkson LLP Park View House 58 The Ropewalk Nottingham NG1 5DD Nottingham NG1 5DD (GB)