(19)
(11) EP 2 203 460 A1

(12)

(43) Date of publication:
07.07.2010 Bulletin 2010/27

(21) Application number: 08780519.8

(22) Date of filing: 11.04.2008
(51) International Patent Classification (IPC): 
C07F 9/576(2006.01)
C07F 9/6503(2006.01)
(86) International application number:
PCT/US2008/060051
(87) International publication number:
WO 2008/128056 (23.10.2008 Gazette 2008/43)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
Designated Extension States:
AL BA MK RS

(30) Priority: 12.04.2007 US 911426 P

(71) Applicant: The Board of Trustees of the University of Illinois
Urbana, Illinois 61801 (US)

(72) Inventors:
  • OLDFIELD, Eric
    Champaign, IL 61821 (US)
  • ZHANG, Yonghui
    Urbana, IL 61801 (US)
  • YIN, Fenglin
    Naperville, IL 60540 (US)

(74) Representative: Lord, Hilton David et al
Marks & Clerk LLP 90 Long Acre
London WC2E 9RA
London WC2E 9RA (GB)

   


(54) BISPHOSPHONATE COMPOUNDS AND METHODS WITH ENHANCED POTENCY FOR MULTIPLE TARGETS INCLUDING FPPS, GGPPS, AND DPPS