METHODS OF ADMINISTERING N-(5-TERT-BUTYL-ISOXAZOL-3-YL)-N'-{4-Ý7-(2-MORPHOLIN-4-YL-ETHOXY)IMIDAZOÝ2,1-B¨Ý1,3¨BENZOTHIAZOL-2-YL¨PHENYL}UREA TO TREAT PROLIFERATIVE DISEASE - Patent 2205244

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EP 2 205 244 A1

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(43)	Date of publication:
	14.07.2010 Bulletin 2010/28

(21)	Application number: 08847113.1

(22)	Date of filing: 07.11.2008

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International Patent Classification (IPC):

A61K 31/5377^(2006.01)
A61P 35/02^(2006.01)

A61P 35/00^(2006.01)

(86)	International application number:
	PCT/US2008/012539

(87)	International publication number:
	WO 2009/061446 (14.05.2009 Gazette 2009/20)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
	Designated Extension States:
	AL BA MK RS

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Priority:

08.11.2007 US 2583
07.12.2007 US 5803
19.09.2008 US 98676
06.11.2008 US 112060

(71)	Applicant: Ambit Biosciences Corporation
	San Diego, CA 92121 (US)

(72)	Inventors:
	JAMES, Joyce, K. San Diego CA 92109 (US) EICHELBERGER, Shawn R. San Diego, CA 92121 (US) SAVALL, Traci L. San Diego, CA 92121 (US)

(74)	Representative: Ritter, Thomas Kurt
	Jones Day Prinzregentenstraße 11 80538 München 80538 München (DE)

(54)	METHODS OF ADMINISTERING N-(5-TERT-BUTYL-ISOXAZOL-3-YL)-N'-{4-Ý7-(2-MORPHOLIN-4-YL-ETHOXY)IMIDAZOÝ2,1-B¨Ý1,3¨BENZOTHIAZOL-2-YL¨PHENYL}UREA TO TREAT PROLIFERATIVE DISEASE