SYNTHESIS OF OLIGONUCLEOTIDES OR PHOSPHOROTHIOATE OLIGONUCLEOTIDE WITH A CAPPING AGENT OF N-METHYLIMIDAZOLE FREE OF 1,3,5-TRIMETHYLHEXAHYDRO-1,3,5-TRIAZINE - Patent 2205619

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EP 2 205 619 A1

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(43)	Date of publication:
	14.07.2010 Bulletin 2010/28

(21)	Application number: 08840574.1

(22)	Date of filing: 13.10.2008

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International Patent Classification (IPC):

C07H 21/04^(2006.01)

C07H 21/00^(2006.01)

(86)	International application number:
	PCT/US2008/079678

(87)	International publication number:
	WO 2009/052034 (23.04.2009 Gazette 2009/17)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
	Designated Extension States:
	AL BA MK RS

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Priority:

15.10.2007 US 980063 P
10.10.2008 US 224953

(71)	Applicant: Honeywell International Inc.
	Morristown, NJ 07962-2245 (US)

(72)	Inventors:
	LORENZ, Sandra Grant Haven Michigan 49441 (US) PRZYBYTEK, Jim West Olive Michigan 49460 (US) SNOBLE, Karel Norton Shores Michigan 49441 (US)

(74)	Representative: Hucker, Charlotte Jane
	Kilburn & Strode 20 Red Lion Street London WC1R 4PJ London WC1R 4PJ (GB)

(54)	SYNTHESIS OF OLIGONUCLEOTIDES OR PHOSPHOROTHIOATE OLIGONUCLEOTIDE WITH A CAPPING AGENT OF N-METHYLIMIDAZOLE FREE OF 1,3,5-TRIMETHYLHEXAHYDRO-1,3,5-TRIAZINE