(19)

(11)

EP 2 205 738 A2

(12)

(88) Date of publication A3: 09.07.2009 (43) Date of publication: 14.07.2010 Bulletin 2010/28 (21) Application number: 08804580.2 (22) Date of filing: 23.09.2008

(51) International Patent Classification (IPC):  C12N 15/11(2006.01) (86) International application number: PCT/EP2008/062658 (87) International publication number: WO 2009/043759 (09.04.2009 Gazette 2009/15)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 04.10.2007 US 977409 P 19.03.2008 WO PCT/EP2008/053314 (71) Applicant: Santaris Pharma A/S 2970 Hørsholm (DK)	(72) Inventors: HEDTJÄRN, Maj DK-2450 Copenhagen (DK) HANSEN, Jens Bo DK-2920 Charlottenlund (DK) (74) Representative: Wroe, Stephanie et al D Young & Co LLP 120 Holborn London EC1N 2DY London EC1N 2DY (GB)