(19)

(11)

EP 2 205 756 A2

(12)

(88) Date of publication A3: 23.07.2009 (43) Date of publication: 14.07.2010 Bulletin 2010/28 (21) Application number: 08806500.8 (22) Date of filing: 01.10.2008

(51) International Patent Classification (IPC):  C12Q 1/00(2006.01) G06F 19/00(2006.01) (86) International application number: PCT/GB2008/003355 (87) International publication number: WO 2009/044156 (09.04.2009 Gazette 2009/15)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 03.10.2007 GB 0719252 (71) Applicant: Medical Research Council 20 Park Crescent London W1B 1AL (GB)	(72) Inventors: MCMAHON, Harvey Cambridge CB2 0QH (GB) DOHERTY, Gary Garvagh, Co Derry N Ireland BT51 5NB (GB) LUNDMARK, Richard 906 41 Urneå (SE) DAUMKE, Oli 13092 Berlin (DE) (74) Representative: Richards, William John et al Bryer, Shelley, John Amor, Greenwood LLP 7 Gay Street Bath BA1 2PH Bath BA1 2PH (GB)