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(11)

EP 2 209 769 A1

(12)

(43) Date of publication: 28.07.2010 Bulletin 2010/30 (21) Application number: 08842725.7 (22) Date of filing: 23.10.2008

(51) International Patent Classification (IPC):  C07D 215/18(2006.01) A61K 31/573(2006.01) A61P 11/06(2006.01) A61K 31/47(2006.01) A61K 31/58(2006.01) (86) International application number: PCT/CA2008/001875 (87) International publication number: WO 2009/052625 (30.04.2009 Gazette 2009/18)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 25.10.2007 US 342 (71) Applicant: Merck Frosst Canada Ltd. Kirkland, Québec H9H 3L1 (CA)	(72) Inventor: O'SHEA, Paul Kirkland Québec H9H 3L1 (CA) (74) Representative: Hussain, Deeba et al Merck & Co., Inc. Hertford Road Hoddesdon Hertfordshire EN11 9BU Hoddesdon Hertfordshire EN11 9BU (GB)