(19)

(11)

EP 2 211 618 A1

(12)

(43) Date of publication: 04.08.2010 Bulletin 2010/31 (21) Application number: 08838205.6 (22) Date of filing: 10.10.2008

(51) International Patent Classification (IPC):  A01N 43/40(2006.01) A61K 31/445(2006.01) A61K 31/405(2006.01) (86) International application number: PCT/US2008/079447 (87) International publication number: WO 2009/049113 (16.04.2009 Gazette 2009/16)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 11.10.2007 US 979161 P (71) Applicant: Glaxo Group Limited Greenford, Middlesex UB6 0NN (GB)	(72) Inventors: SEHON, Clark, A. King Of Prussia PA 19406 (US) WANG, Gren, Z. King Of Prussia PA 19406 (US) VIET, Andrew, Q. Schwenksville PA 19473 (US) ZHANG, Jing Collegeville Pennsylvania 19426 (US) (74) Representative: Florence, Julia Anne et al GlaxoSmithKline Corporate Intellectual Property CN925.1 980 Great West Road Brentford, Middlesex TW8 9GS Brentford, Middlesex TW8 9GS (GB)