(19)
(11) EP 2 215 054 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
08.02.2012 Bulletin 2012/06

(45) Mention of the grant of the patent:
31.08.2011 Bulletin 2011/35

(21) Application number: 08850350.3

(22) Date of filing: 13.11.2008
(51) International Patent Classification (IPC): 
C07C 311/08(2006.01)
C07D 239/94(2006.01)
C07D 471/04(2006.01)
A61K 31/47(2006.01)
A61K 31/497(2006.01)
 C07D 239/72(2006.01)
C07D 401/12(2006.01)
A61K 31/18(2006.01)
A61K 31/436(2006.01)
(86) International application number:
PCT/US2008/012763
(87) International publication number:
WO 2009/064449 (22.05.2009 Gazette 2009/21)

(54)

AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME

AMIDDERIVATE ALS IONENKANALLIGANDEN SOWIE PHARMAZEUTISCHE ZUSAMMENSETZUNGEN UND VERWENDUNGSVERFAHREN DAFÜR

DÉRIVÉS AMIDE À TITRE DE LIGANDS DES CANAUX IONIQUES ET COMPOSITIONS PHARMACEUTIQUES ET PROCÉDÉS D'UTILISATION CORRESPONDANTS

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

(30) Priority: 13.11.2007 US 2838

(43) Date of publication of application:
11.08.2010 Bulletin 2010/32

(73) Proprietors:
  • Evotec AG
    22525 Hamburg (DE)
  • Pfizer Global Research and Development
    Kent CT13 9NJ (GB)

(72) Inventors:
  • COX, Matthew
    San Francisco CA 94117 (US)
  • O'MAHONY, Donogh John, Roger
    San Mateo CA 94401 (US)
  • ESTIARTE-MARINEZ, Maria, De Los Angeles
    San Francisco CA 94110 (US)
  • KAWASHIMA, Tadashi
    Sandwich Kent CT13 9NJ (GB)
  • NAGAYAMA, Satoshi
    Tokyo 151-8589 (JP)
  • SHISIDO, Yuji
    Chita-gun, Aichi-ken, 470-238 (JP)
  • TANAKA, Hirotaka
    Tokushima-shi, Tokushima-ken 770-0006 (JP)
  • DUNCTON, Matthew, Alexander, James
    San Bruno CA 94066 (US)
  • CALABRESE, Andrew, Antony
    San Diego CA 92121 (US)

(74) Representative: Büchel, Edwin 
Isenbruck Bösl Hörschler LLP Patentanwälte Eastsite One Seckenheimer Landstraße 4
68163 Mannheim
68163 Mannheim (DE)


(56) References cited: : 
WO-A-2005/003084
WO-A-2007/041634
 WO-A-2006/097817
US-B1- 6 380 218
   
       
    Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).