(19)

(11)

EP 2 217 576 A2

(12)

(88) Date of publication A3: 16.07.2009 (43) Date of publication: 18.08.2010 Bulletin 2010/33 (21) Application number: 08847030.7 (22) Date of filing: 06.11.2008

(51) International Patent Classification (IPC):  C07D 243/18(2006.01) C07D 243/12(2006.01) C07D 243/10(2006.01) (86) International application number: PCT/US2008/082629 (87) International publication number: WO 2009/061916 (14.05.2009 Gazette 2009/20)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 06.11.2007 US 985898 P (71) Applicant: The Regents of the University of Michigan Ann Arbor, MI 48104-2592 (US)	(72) Inventor: GLICK, Gary, D. Ann Arbor MI 48103 (US) (74) Representative: Witte, Weller & Partner  Phoenixbau Königstrasse 5 70173 Stuttgart 70173 Stuttgart (DE)