(19)

(11)

EP 2 217 616 A1

(12)

(43) Date of publication: 18.08.2010 Bulletin 2010/33 (21) Application number: 08856375.4 (22) Date of filing: 05.12.2008

(51) International Patent Classification (IPC):  C07K 14/195(2006.01) C12N 15/82(2006.01) (86) International application number: PCT/NL2008/050775 (87) International publication number: WO 2009/072883 (11.06.2009 Gazette 2009/24)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 05.12.2007 EP 07122354 (71) Applicant: KEYGENE N.V. 6708 PW Wageningen (NL)	(72) Inventors: BRUGGEMAN, Ilona Margaretha NL-6702 CW Wageningen (NL) DE BOTH, Michiel Theodoor Jan NL-6708 BG Wageningen (NL) (74) Representative: Swinkels, Bart Willem et al Nederlandsch Octrooibureau J. W. Frisolaan 13 2517 JS Den Haag 2517 JS Den Haag (NL)