(19)

(11)

EP 2 219 615 A2

(12)

(88) Date of publication A3: 04.06.2009 (43) Date of publication: 25.08.2010 Bulletin 2010/34 (21) Application number: 08838925.9 (22) Date of filing: 15.10.2008

(51) International Patent Classification (IPC):  A61K 9/16(2006.01) A61K 31/195(2006.01) A61K 31/7032(2006.01) A61K 9/72(2006.01) A61K 31/52(2006.01) (86) International application number: PCT/EP2008/063916 (87) International publication number: WO 2009/050217 (23.04.2009 Gazette 2009/17)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 15.10.2007 EP 07118508 (71) Applicant: Laboratoires SMB 1080 Bruxelles (BE)	(72) Inventors: VANDERBIST, Francis B-1650 Beersel (BE) BAUDIER, Philippe B-1180 Uccle (BE) AMIGHI, Karim B-1150 Woluwé Saint Pierre (BE) PILCER, Gabrielle B-2018 Antwerpen (BE) (74) Representative: Vandeberg, Marie-Paule L.G. et al Office Kirkpatrick S.A. Avenue Wolfers 32 1310 La Hulpe 1310 La Hulpe (BE)