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EP 2 219 645 A2

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(88) Date of publication A3: 27.08.2009 (43) Date of publication: 25.08.2010 Bulletin 2010/34 (21) Application number: 08851028.4 (22) Date of filing: 13.11.2008

(51) International Patent Classification (IPC):  A61K 31/404(2006.01) A61K 31/4439(2006.01) A61K 45/06(2006.01) A61P 11/06(2006.01) A61P 37/08(2006.01) A61K 31/405(2006.01) A61K 31/4709(2006.01) A61P 27/14(2006.01) A61P 17/00(2006.01) (86) International application number: PCT/GB2008/003824 (87) International publication number: WO 2009/063202 (22.05.2009 Gazette 2009/21)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 13.11.2007 GB 0722203 (71) Applicant: Oxagen Limited Oxfordshire OX14 4RY (GB)	(72) Inventors: HUNTER, Michael, George Abingdon, Oxon OX14 4RY (GB) PETTIPHER, Eric, Roy Abingdon, Oxon OX14 4RY (GB) PERKINS, Colin, Michael Abingdon, Oxon OX14 4RY (GB) Payton, Mark, Anthony Abingdon, Oxon OX14 4RY (GB) XUE, Luzheng Abingdon, Oxon OX14 4RY (GB) (74) Representative: Roberts, Alison Christine et al Kilburn & Strode LLP 20 red Lion Street London WC1R 4PJ London WC1R 4PJ (GB)