(19)

(11)

EP 2 224 806 A1

(12)

(43) Date of publication: 08.09.2010 Bulletin 2010/36 (21) Application number: 08862226.1 (22) Date of filing: 16.12.2008

(51) International Patent Classification (IPC):  A01N 43/42(2006.01) A61K 31/44(2006.01) (86) International application number: PCT/US2008/087030 (87) International publication number: WO 2009/079518 (25.06.2009 Gazette 2009/26)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 17.12.2007 US 7882 P (71) Applicant: Alpharma Pharmaceuticals LLC Bridgewater, PA 08807 (US)

(72) Inventors: LIANG, Alfred Bridgewater PA 08807 (US) MATTHEWS, Frank Bridgewater PA 08807 (US) BOEHM, Garth Bridgewater PA 08807 (US) TANG, Lijuan Bridgewater PA 08807 (US) JOHNSON, Frank Bridgewater PA 08807 (US) STAUFFER, Joseph Bridgewater PA 08807 (US) (74) Representative: Sahans, Sarah Anne et al HLBBshaw Merlin House Falconry Court Baker's Lane Epping, Essex CM16 5DQ Epping, Essex CM16 5DQ (GB)