(19)

(11)

EP 2 227 232 A1

(12)

(43) Date of publication: 15.09.2010 Bulletin 2010/37 (21) Application number: 08859050.0 (22) Date of filing: 08.12.2008

(51) International Patent Classification (IPC):  A61K 31/472(2006.01) A61P 37/02(2006.01) A61P 31/00(2006.01) A61P 37/00(2006.01) A61P 29/00(2006.01) A61P 43/00(2006.01) (86) International application number: PCT/US2008/013509 (87) International publication number: WO 2009/075822 (18.06.2009 Gazette 2009/25)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 07.12.2007 US 5869 P (71) Applicant: Fibrogen, Inc. San Francisco, CA 94158 (US)	(72) Inventors: CHOW, Felice, Aisha San Francisco CA 94158 (US) KLAUS, Stephen, J. San Francisco CA 94158 (US) LANGSETMO PAROBOK, Ingrid San Francisco CA 94158 (US) (74) Representative: Goodfellow, Hugh Robin  Carpmaels & Ransford One Southampton Row London WC1B 5HA London WC1B 5HA (GB)