(19)
(11) EP 2 229 377 A1

(12)

(43) Date of publication:
22.09.2010 Bulletin 2010/38

(21) Application number: 08859530.1

(22) Date of filing: 12.12.2008
(51) International Patent Classification (IPC): 
C07D 401/12(2006.01)
A61K 31/465(2006.01)
A61P 17/06(2006.01)
A61P 37/00(2006.01)
 C07D 401/14(2006.01)
A61P 11/06(2006.01)
A61P 29/00(2006.01)
(86) International application number:
PCT/US2008/086594
(87) International publication number:
WO 2009/076602 (18.06.2009 Gazette 2009/25)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
Designated Extension States:
AL BA MK RS

(30) Priority: 13.12.2007 US 13457 P

(71) Applicant: Wyeth LLC
Madison, NJ 07940 (US)

(72) Inventors:
  • TUMEY, Lawrence, Nathan
    Pawcatuck, Connecticut 06379 (US)
  • BOSCHELLI, Diane, Harris
    New City NY 10956 (US)
  • BHAGIRATH, Niala
    Kew Gardens Hills NY 11367 (US)
  • CHEN, Joan, Jowen
    Flushing NY 11358 (US)
  • FLOYD, Middleton, Brawner, Jr.
    Suffern NY 10901 (US)
  • LI, Zhong
    Congers NY 10920 (US)
  • NIU, Chuansheng
    Cheshire CT 06410 (US)
  • SHIM, Jaechul
    Oakland NJ 07436 (US)
  • WANG, Yan
    Tenafly NJ 07670 (US)
  • WANG, Yanong, Daniel
    Warren NJ 07059 (US)
  • WU, Biqi
    Nanuet NY 10954 (US)
  • EID, Clark, N. Jr.
    New City NY 10956 (US)

(74) Representative: Motion, Keith Robert 
Pfizer Limited European Patent Department Ramsgate Road
Sandwich, Kent CT13 9NJ
Sandwich, Kent CT13 9NJ (GB)

   


(54) 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS