(19)

(11)

EP 2 234 619 A2

(12)

(88) Date of publication A3: 28.01.2010 (43) Date of publication: 06.10.2010 Bulletin 2010/40 (21) Application number: 09731572.5 (22) Date of filing: 10.04.2009

(51) International Patent Classification (IPC):  A61K 31/573(2006.01) A61K 47/34(2006.01) A61P 19/00(2006.01) A61K 9/00(2006.01) (86) International application number: PCT/US2009/040234 (87) International publication number: WO 2009/129148 (22.10.2009 Gazette 2009/43)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA RS (30) Priority: 18.04.2008 US 46218 02.03.2009 US 396122 18.04.2008 US 105864 (71) Applicants: Medtronic, Inc. Minneapolis, MN 55432 (US) Warsaw Orthopedic, Inc. Warsaw, Indiana 46581 (US)	(72) Inventors: KING, Vanja, Margareta Memphis TN 38104 (US) ZANELLA, John, Myers Cordova TN 38018 (US) WILSEY, Jared, T. Memphis TN 38103 (US) (74) Representative: O'Connell, Maura et al FRKelly 27 Clyde Road Ballsbridge Dublin 4 Dublin 4 (IE)