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(11)

EP 2 234 983 A1

(12)

(43) Date of publication: 06.10.2010 Bulletin 2010/40 (21) Application number: 08861246.0 (22) Date of filing: 18.12.2008

(51) International Patent Classification (IPC):  C07D 235/02(2006.01) A61K 31/4184(2006.01) A61P 9/06(2006.01) (86) International application number: PCT/US2008/087459 (87) International publication number: WO 2009/079630 (25.06.2009 Gazette 2009/26)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 19.12.2007 US 14937 P (71) Applicant: Wyeth LLC Madison, NJ 07940 (US)	(72) Inventors: BLASS, Benjamin, E. Eagleville Pennsylvania 19403 (US) JANUSZ, John, M. West Chester Ohio 45069 (US) RIDGEWAY, James, M. II Batavia Ohio 45103 (US) WU, Shengde West Chester Ohio 45069 (US) (74) Representative: Cosway, Sarah Michelle  Pfizer Limited European Patent Department Ramsgate Road Sandwich, Kent CT13 9NJ Sandwich, Kent CT13 9NJ (GB)