(19)

(11)

EP 2 235 032 A2

(12)

(88) Date of publication A3: 24.12.2008 (43) Date of publication: 06.10.2010 Bulletin 2010/40 (21) Application number: 08763854.0 (22) Date of filing: 05.05.2008

(51) International Patent Classification (IPC):  C07H 17/04(2006.01) A61P 9/10(2006.01) A61K 31/7048(2006.01) (86) International application number: PCT/IT2008/000303 (87) International publication number: WO 2008/136037 (13.11.2008 Gazette 2008/46)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 04.05.2007 IT MI20070903 04.05.2007 IT MI20070904 (71) Applicants: Università Degli Studi Magna Graecia Di Catanzaro 88100 Catanzaro (CZ) (IT) Universita' Della Calabria 87036 Arcavacata Rende (CS) (IT)	(72) Inventors: PROCOPIO, Antonio I-88100 Catanzaro (IT) SINDONA, Giovanni I-87036 Rende (IT) COSTA, Nicola I-88060 Sant'Andrea (CZ) (IT) GASPARI, Marco I-87100 Cosenza (IT) NARDI, Monica I-87017 Roggiano Gravina (CS) (IT) (74) Representative: Perrotta, Aldo et al Abaty & Neumann srl Corso Umberto 81 88068 Soverato 88068 Soverato (IT)