(19)

(11)

EP 2 235 053 A1

(12)

(43) Date of publication: 06.10.2010 Bulletin 2010/40 (21) Application number: 08839467.1 (22) Date of filing: 17.10.2008

(51) International Patent Classification (IPC):  C07K 14/47(2006.01) (86) International application number: PCT/US2008/080325 (87) International publication number: WO 2009/052390 (23.04.2009 Gazette 2009/17)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 19.10.2007 US 981470 P 19.10.2007 US 981471 P 19.10.2007 US 981473 P 16.04.2008 US 104408 16.04.2008 US 104410 16.04.2008 US 104413 (71) Applicant: Abbott Laboratories Abbott Park, Illinois 60064-6008 (US)	(72) Inventors: TU, Bailin Libertyville Illinois 60048 (US) TYNER, Joan D. Beach Park Illinois 60087 (US) (74) Representative: Modiano, Micaela Nadia et al Modiano & Partners Thierschstrasse 11 80538 München 80538 München (DE)