(19)

(11)

EP 2 242 748 A1

(12)

(43) Date of publication: 27.10.2010 Bulletin 2010/43 (21) Application number: 09701462.5 (22) Date of filing: 09.01.2009

(51) International Patent Classification (IPC):  C07D 233/84(2006.01) A61P 3/10(2006.01) A61K 31/4178(2006.01) A61P 25/04(2006.01) (86) International application number: PCT/US2009/030594 (87) International publication number: WO 2009/089448 (16.07.2009 Gazette 2009/29)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA RS (30) Priority: 11.01.2008 US 20458 (71) Applicant: ALLERGAN, INC. Irvine, CA 92612 (US)	(72) Inventors: AMBRUS, Gyorgy, F. Irvine CA 92606 (US) RUBINO, Mark, P. Irvine CA 92604 (US) HEIDELBAUGH, Todd, M. Fountain Valley CA 92708 (US) NGUYEN, Phong, X. Placentia CA 92870 (US) (74) Representative: HOFFMANN EITLE  Patent- und Rechtsanwälte Arabellastrasse 4 81925 München 81925 München (DE)